Article original·2026

[EN] Fexinidazole versus NECT for stage 2 Trypanosoma brucei gambiense human African trypanosomiasis: a multicentre, randomised, phase III trial

The Lancet Infectious Diseases — Vol. 26 — N° 4 — pp. 412-423

Abstract

This multicentre randomised phase III trial demonstrates non-inferiority of oral fexinidazole compared to the standard NECT regimen for stage 2 HAT, with a cure rate of 95.2% vs 93.8% at 18 months.

Bibliographic reference

Reference

The Lancet Infectious Diseases

Publication date

2026-01-10

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